Form 483

Shionogi Pharma Co., Ltd. Form 483, 2025-07-01

FDA issued a Form 483 to Shionogi Pharma Co., Ltd. on 2025-07-01 with 4 public-safe observations.

483· Form 483 issuedHuman Drugs4 observations

Shionogi Pharma Co., Ltd. · Isawa-Gun, Japan · Issued July 1, 2025

Overview

  • 4 public-safe observations are available for this inspection.
  • 3 structured CFR citations are represented.
  • 2 investigators are tied to this Form 483.

Inspectional observations

Each observation cites the regulation FDA found the firm out of compliance with.

1 Jul 2025
21 CFR 211.113(b)

Procedures for sterile drug products

Cited by Anastasia M Shields, Jessica S Estriplet

1 Jul 2025
21 CFR 211.113(b)

Validation lacking for sterile drug products

Cited by Anastasia M Shields, Jessica S Estriplet

1 Jul 2025
21 CFR 211.42(c)(10)(v)

Cleaning System

Cited by Anastasia M Shields, Jessica S Estriplet

1 Jul 2025
21 CFR 211.42(c)(5)

Mfg / Processing Operations Area

Cited by Anastasia M Shields, Jessica S Estriplet

Inspected site

SPShionogi Pharma Co., Ltd.Isawa-Gun, Japan

Inspection team

Cited regulations

CFR citations associated with this Form 483.

CitationWhat it coversCited
21 CFR 211.113(b)Cited across public-safe Form 483 observations2x
21 CFR 211.42(c)(10)(v)Cited across public-safe Form 483 observations1x
21 CFR 211.42(c)(5)Cited across public-safe Form 483 observations1x

Source document

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Form 483 source document

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Full 483 report

Get the verbatim text of all 4 observations

The source PDF, so your team sees exactly what was cited and how it was answered.

  • The site's full inspection history around this Form 483
  • Whether these citations escalated to a warning letter
  • The investigators involved and the citations they repeat elsewhere