Form 483

Charles River Laboratories Form 483, 2018-06-28

FDA issued a Form 483 to Charles River Laboratories on 2018-06-28 with 10 public-safe observations.

483· Form 483 issuedHuman Drugs10 observations

Charles River Laboratories · Mattawan, United States · Issued June 28, 2018

Overview

  • 10 public-safe observations are available for this inspection.
  • 5 structured CFR citations are represented.
  • 2 investigators are tied to this Form 483.

Inspectional observations

Each observation cites the regulation FDA found the firm out of compliance with.

28 Jun 2018
21 CFR 58.130(e)

Conduct: changes in automated data entries

Cited by Mark J Seaton, Corey K Reno

28 Jun 2018
21 CFR 58.185(a)(9)

Final report: circumstances affecting data qual., integrity

Cited by Mark J Seaton, Corey K Reno

28 Jun 2018
21 CFR 58.33(b)

Study director: all data recorded and verified

Cited by Mark J Seaton, Corey K Reno

28 Jun 2018
21 CFR 58.35(b)(5)

QAU: authorize deviations from protocols or SOPs

Cited by Mark J Seaton, Corey K Reno

28 Jun 2018
21 CFR 58.41

Facility: suitable size and construction

Cited by Mark J Seaton, Corey K Reno

Inspected site

CRCharles River LaboratoriesMattawan, United States

Inspection team

CKCorey K Reno

Cited regulations

CFR citations associated with this Form 483.

CitationWhat it coversCited
21 CFR 58.130(e)Cited across public-safe Form 483 observations2x
21 CFR 58.185(a)(9)Cited across public-safe Form 483 observations2x
21 CFR 58.33(b)Cited across public-safe Form 483 observations2x
21 CFR 58.35(b)(5)Cited across public-safe Form 483 observations2x
21 CFR 58.41Cited across public-safe Form 483 observations2x

Full 483 report

Get the verbatim text of all 10 observations

The full inspection record, as Atlas holds it, so your team sees exactly what was cited and how it was answered.

  • The site's full inspection history around this Form 483
  • Whether these citations escalated to a warning letter
  • The investigators involved and the citations they repeat elsewhere